Introduction: Coffee is one of the most consumed beverages worldwide and it contains several biologically active components which may have an impact on human health. Aim: This is an experimental study designed to evaluate the effect of coffee intake on plasma glucose and serum lipid profile levels in male students of College of Health Science, Anambra State, Nigeria. Methods: A total of 30 male participants aged between eighteen (18) and thirty (30) years were randomly recruited for the study. Five milliliters (5mls) of baseline samples (after an overnight fast) were collected from participants at day 0 as baseline samples and levels of glucose and lipid profile were evaluated. Subsequently, in addition to their normal diet, each of the participants received a cup of caffeinated coffee prior to their breakfast daily for a period of 21 days.After overnight fasting, post research (test 1st & 2nd) samples (fasting blood sample) were collected on days 11 and 22 respectively and the levels of glucose and lipid profile were re-evaluated. Plasma glucose and lipid concentrations were determined using enzymatic methods respectively. Also, the body mass index (BMI) and blood pressure readings of participants were determined before and after coffee consumption. Results: The results showed that there were significant increases in the mean plasma glucose and serum HDL-C concentrations 11 days (intermediate consumption) and 22 days (post consumption) following coffee intake when compared with baseline levels respectively (p<0.05). However, the mean BMI, SBP, DBP and serum levels of TC, TG and LDL-C remained unaltered after coffee consumption (p>0.05) respectively. Conclusion: The present study has shown that short term consumption of coffee may cause significant alterations in plasma concentration of glucose and serum HDL-C levels with no significant effects on BMI and serum concentrations of TC, TG and LDL-C. However, further studies using larger population size may be necessary in validating these findings.

Author Name: Ihim AC, Nwanua MI, Ogbodo EC, Meludu SC

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Keywords: Coffee, Plasma glucose, lipid profile, diabetes, cardiovascular diseases

ISSN: 1116-1043

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