In this study Cytotoxic effects of radioiodine (I131) which is a radionuclide used for the diagnosis and treatment of thyroid cancers and hyperthyroidism on mitotic chromosomes of root tips meristematic cells of fava bean [Vicia faba L. (Fabaceae)] were investigated. Seeds treated with radioiodine (I131) for 24, 48, 96 hours and 16 days were germinated. The root tips were taken and prepared for microscopic studies. Radioiodine (I131) caused chromosomal abnormalities as chromosome adherence, chromosome breaks, ring chromosome, chromatin bridge in V. faba L. root tip cells. The most common type of observed abnormalities was fish bone chromosome adherence, ring and C chromosome and chromosome dispersion. As a result of this study, it was determined that radioiodine (I131) had a mitodepressive effect on mitosis and harmful effects on V. faba L. root tip cells. The data obtained were evaluated numerically and statistical analysis was performed.
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Author Name: Yasemin PARLAK; Didem GÖKSOY; Bahattin BOZDA?; Ali ÖZDEM?R; Gözde MUTEVEL?ZADE; Kamuran AKTA?; Gül GÜMÜ?ER; Elvan SAY?T; Canan ÖZDEM?R
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Keywords: Vicia faba L., fava bean, chromosome abnormalities, radioiodine(I131).
ISSN: 1300-0225
EISSN: 2667-6087
EOI/DOI: 10.18615/anadolu.727244
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