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EVALUATION OF CLINICAL EFFICACY AND SAFETY OF ZANOPAUSE TABLET AN HERBAL FORMULATION IN PRE-MENOPAUSAL AND MENOPAUSAL WOMEN

Abstract Background: To evaluate the clinical efficacy and safety effect of Zanopause tablet a marketed herbal formulation of Emami Ltd., in pre-menopausal and menopausal women. Methods: 50 women patients age range between 40 to 70 years old suffering from pre-menopausal and menopausal symptoms like hot flashes, night sweats, irregular periods, loss of libido, vaginal dryness and mood swings. Zanopause tablet was given twice a day for 60 days. Results: A significant improvement was observed in clinical symptoms like hot flashes, night sweats, irregularity of periods, loss of libido, vaginal dryness and mood swings after ZZT medication. Laboratory investigation showed improved Haemotological levels in all the patients. Other parameters were observed in normal range. On ‘0th’ day 7.6 - 14.1 (G %), 8.1 – 14.7 (G %) on 45th day and 8.7 – 15.2 (G %) on 60th day. ZZT medication showed a significant increase in Haemoglobin level of patients. 5200 - 9900 (/cu.mm.) on ‘0th’ day, 5600 - 1100 (/ cu.mm.) on 45th day and 4.01-5800 - 9700 (/ cu.mm.) on 60th day, WBC count was observed in normal range, from the data obtained from blood samples of 50 patients. Upper Abdomen USG was normal in all the 50 patients. Conclusion: Menopause symptoms like hot flashes, night sweats, irregularity of periods, loss of libido, vaginal dryness were taken care off. Increase in Haemoglobin levels and status of wellbeing. Reduce pain in knee joints were observed.



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Keywords: Zanopause tablet, Pre-menopausal and Menopausal symptoms

ISSN: 2394-2746

EISSN: 2394-2754


EOI/DOI: 01/12/2014


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