Toxic metals like Cd and Pb pose the greatest ecological threat to ecosystems, especially in and around the industrial cities. Four farms located around Kharkiv industrial city were chosen for scientific experiments carried out on cows feeding specially developed antidote (mineral-vitamin premix "MP-A") and subcutaneous injection of biologically active preparation "BP-9". These novelty products enhanced the urinary excretion of heavy metals Cd, Pb, Cu and Zn while ensuring the production of high quality environmentally safe milk. The toxicants are absorbed from the gastrointestinal tract into the blood, travel across the body, accumulate in organs and tissues, and pass through urine and milk. The accumulation of Cd in the blood of tested cows in control group was, on average, from 77.94 to 101.20 nmol/L, and of Pb from 4.63 to 8.32 μmol/L. The transfer of Cd from blood to urine was, on average, 1.7%-2.0%, and of Pb 5.4-7.3%. The antidote substances contributed to the exacerbation of heavy metal extermination from the body of animals and the restoration of its homeostasis. The transfer of Cd from blood to urine averaged 3.9% to 9.5% and of Pb 37.7% to 103.5% in second experimental group of cows. The same for Cd was 7.1% to 12.7% and for Pb was 70.7% to 144.1% in third experimental group. The mineral-vitamin premix and biopreparation BP-9 blocked absorption of the pollutants into the gastrointestinal tract, strengthened the protective effects on organs, and facilitated the elimination of heavy metals through urine. Dairy productivity of animals also increased in cows of the second and third experimental groups by 17-22 kg per day compared to the control group having 14 kg per day (P<0.01).

Author Name: Serhii Portiannyk, Oleksii Mamenko

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Keywords: Remix; Biopreparation; Medicinal plants; Heavy metals; Contaminated feeds; Antidote substances; Animal productivity

ISSN: 2581-6853

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EOI/DOI: 10.33002/nr2581.6853.040411

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