There are four IL-1 Receptor-Associated Kinase (IRAK) family members in mammals, one of which is IRAK1. IRAK1 interacts with IRAK4, which is associated with MyD88 adaptor protein upon ligand stimulation. This research aims to study the domains of IRAK1, understanding of which is important to yield insights into the functional role of IRAK1 in the pathogen sensing mechanism. The results obtained from this study may guide further research in the immunotherapy studies on the Toll-Like Receptor (TLR) signaling pathway.
Real Time Impact Factor:
1.66667
Author Name: Sim-Hui Tee
URL: View PDF
Keywords: Bioinformatics; Gene; Protein; IRAK1; Domain Analysis; Kinase
ISSN: 2326-5825
EISSN: 2326-5833
EOI/DOI:
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