Recently, a new fabrication method of scaffolds based on porous TiNi alloy has been developed for tissue engineering. This provides significant advantages over conventional scaffolds, including: versatility, reproducibility and industrial scalability. Structural properties of porous TiNi-based scaffolds have been investigated. The microporous surface of walls was shown to create the condition for cells adhesion and ingrowth, it facilitates the penetration of nutrients from outside and metabolite’s outflow during the study. Features of cell growth, which makes different tissue populations and step-by-step cellular interaction with the porous- permeable structure of TiNi-based scaffold were established. Methods used in this study proved the tissue ingrowth within scaffold’s pores. Cells implanted to be well protected from the allogenic environment were comprehensively found in vitro to fill all the pore space and to create specific tissues.
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Author Name: Kokorev O.V., Hodorenko V.N., Chekalkin T.L., Dambaev G.Ts., Gunther V.E.
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Keywords: Biomaterials, Tissue Engineering, Porous TiNi-based Scaffold
ISSN: 09769595
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